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AFAIK, for those sorts of diseases, it doesn't matter, but only past Herbal meds. IOW - They have to get some sort of medicine, but it doesn't matter what grade it is as far as the required number of "Treatments" are reached.
https://rimworldwiki.com/wiki/Disease
So, basically, five treatments with Herbal Medicine will cure Gut Worms. As far as "Qualtiy" of medicine goes, I think that was confirmed to not really be an issue, only the number of treatments matter. Though, if someone treating the disease fails, that would probably not count as a Treatment.
(I'm still a "Noob" but I remember having questions about this, as well, and went looking for answers and the info above is what I found to be generally acknowledged as "true.")
So while having the worms for a year sounds kinda absurd, the little test I did, did say it might be possible.
@Jigain - how did you come up with the 300% total on healing?
https://rimworldwiki.com/wiki/Gut_worms
Also, if you're talking about penoxycyline, those aren't antibiotics. Antibiotics implies it's a reactive treatment, but penoxycyline is a preventative one. Take it, and your pawn cannot get a new infection of the prevented type. But if they already have one, even if it's in its initial hidden stage, penoxycyline will do naught.