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The others are for role-play but for Lithoids you don't really get that much benefit from bio ascension.
With clone armies who stick to the 100 pop cap can then become the rulers of the empire and then have a smaller race with rights to be leaders and then turn your worker bees into mind stapled chattal slaves for huge resources while having either a race with rights but preferably an indentured servant for a while if for nothing else but organization. Once your planets are organized how you want to you can remove nerve stapled, free your slaves and give them full rights and they'll be in the jobs you want them and your output will spike because of high happiness pops that are ultra specialized.
TLDR: Psionic is best early game, bio is best mid game and machine is best end game. But all of them do give good bonuses, and some empires will benefit far more from one than the other.
It's not just the min-maxing, but the pop management of a single Synth species is so much more comfortable than the other 2 options.
Agree on the single pop thing, but some empires manage very well with multiple species (Clone and Necrophage are good examples of this) where you can get some amazing bonuses and with the way you can stack pop growth mid game on ecuminopoli with pleasure seekers you can print massive stacks of unity because you grow all the pops and then do a mass purge of the species you put out. Less unity a turn than crats sure, but the necrophage can take become crisis and just purge 1 pop a month per planet to get unity and ruler pop. Each pop growth world i have will be pushing 80-90 pop growth per month without much issue and can even get into the mid 100's if you go full entertainer with art exhibit and luxury goods (compared to my best thrallworld which with same settings was only getting 14.4 pop gain per month. last game i ended up in an unmodded game with like 70m unity in the bank and all of the planets i had at rank 10 except for one which needed over 70m unity to level up because of how much unity that build makes when i'm purging my empire of pops for main pop (And to fix lag that starts happening about then). I also ended up filling four full ring worlds (2 i stole) with research build for all but one (Which did my entire empire's farming). That was a psychic run, btw and with that bonus a servile i bought on the slave market and a prole (who became battle thrall) that was on one of my 3 inhabited planets from start added to the psychic boost i was getting huge on all outputs. But again, that's a necrophage start which has stupidly good boosts to begin with.
Necrophage builds do have the bonus of slavery early on (Same with servile or some of the cool abilities you can get from primitives), which helps with the management and can add up to some significant boons.
Necrophage is synthetic light.
Nihilist Acquisition is how you grow.
Neutral: Psi
Good synergy: Synth
As noted by the doge, Lithoids dont get much from bio ascension. They cant apply 2 of the 3 unique supertraits. Altho it could still be used for any xenos if you plan on using a lot and cloning vats are still a thing. Bio has huge potential but requires large investment. In real time too, since you need to micromanage species more.
So do you plan on doing conquest or migration? Do you mind using a lot of xenos? If you dont getting xenos then bio can still be very good. But you will only be able to give Erudite to your lithoids, not the other 2 special traits.
Psi has the advantage of being low investment: only project is for the shroud. It takes just 1 tech option that doesnt require a tech path like bio or synth, but its a very rare tech.
Traits are the strongest out of the 3 ascension paths, and you get an extra 5 stability from psicorps. (but only on planets with 25+ pops)
This doesnt have any synergy or lack thereof with lithoids.
Its main downside is really that you can get the leader traits and species traits via other means. Granted it does require a good amount of investment to do that. If you have Psi-ascension all your leaders will retro-actively get the psionic leader traits.
Without the ascension that wont be the case, and you would have to replace all your existing leaders with new ones that have Psionic.
Synth scales the best with Lithoid unique trait. Cyborgs give even more habitability to your lithoids while synths will max it. Synths also remove the growth penalty inherent to lithoids.
If you dont want xenos, well this will make it so none is a xeno. Every species becomes your main species.
Problem with that is Psionic is usually obtained in mid game. At which point you could obtain the Psionic leader trait through other means. (especially when playing as Bio) Idk why they dont remove Psionic being a rare tech, or lower its tier.
And also why Synth dont have a -100% growth penalty on biological growth.
But yeah, I agree, Synth is sooooooooooooo boring, I mean, it's great, no habitability penalties anywhere, great production bonuses, solves the Xeno issue, but it's so bland, there aren't any special mechanics related to this, it's just "Be productive"
Bio and Psi both keep the template but improve on it so they dont have that problem.
I think it would also be cooler if synths kept your original species portrait. To me it also doesnt really make sense that the synthetics wouldnt look similar to your original species.