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It's still the last disease I remove if I have multiples.
It's actually okay in endless, where the ACC penalty is obliterated by repetitions of Jester's Battle Ballad.
If you get rabies, it can be worth not removing it until you get a second disease. Because this:
Standard focus ring: +10 acc +5 crit
Rabies focus ring: +15 dam +5 crit.
Though as per the other posters, you'll want another source of +acc. Another strong trinket, a high-level jester, overlevelled skills, or having high base accuracy. MAAs command is too slow; even after rabies it's better to just hit things with him.
I'm no number cruncher but I do know you can do perfectly fine without it and much prefer not having to add more to consider when I 'could' just slap on a trinket I want instead.