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Just use some AOE attacks and you'll kill it in no time. They're usaully bad in any other case because you want to focus enemies but the unstable flesh has one single HP bar so AOE attacks are OP. Hound's harry, Zealous accusation, plague grenade and Flashing dagger are very good in this fight. especially hound's harry. If you choose single target attacks anyway, focus the heart because it has no PROT.
Essentially once it's shifted, have someone mark the most vulnerable section then everyone who can reach it hammers that bit. Characters like the Leper or Crusader don't always fare too well in this encounter because they're limited to striking at the front ranks (which might have quite high Prot on some rounds). Essentially you want a party where every member can target each and any rank most of the time. The formless flesh does not push or pull your heroes around so you can have some quite positional characters (Like the Arbalest) perform quite reliably without having to worry about them being shuffled out of place.
you want AOE DOTs (as everyone has said). Hellion has some nice bleeds, HM can use harry or hounds rush on weak segments, plague doc can plague grenage or cure/heal you team if you need it. either healer would work, although occultist has more synergy with the party (plus the party can run enough off-heals that aoe vestal heal isn't as required).
hope you have better luck!
But yes the easiest thing to do is to bring a plague doctor and/or jesters, and spam their AOE, largely ignoring the fight mechanics.
The hellion can hit every rank, brings strong bleeds, and has a strong stun for the times it spawns no soft bits.
It's a good idea to bring antivenoms and bandages (for once) to this boss.
I usually go with :
Plague/Vestal/MaA/Hellion
They all get enough HP, I get a lot of stuns if needed (From Plague with Blasphemous Vial, Hellion/MaA), good choice of row hitting with Hellion (Bleed Out can be nice to have too), and the ability to be fully safe on your backlane with the protect of your MaA.
You can also stack the buffs of your MaA, getting dodge + Damage as you camp, and stacking Bolster during the fight when you don't need his stun/protect, to reach a good amount of dodge (50-70+) and get a decent amount of dodging during the fight (even tho the dodge stat isn't quite reliable)