The Binding of Isaac: Rebirth

The Binding of Isaac: Rebirth

alex May 3, 2021 @ 6:23am
T. Cain 100% Winning Strategy
This may require some restarting. I recommend to look up Platinum God and follow the recipes there, since there are different recipes that are better depending on your situation in-game.

Step 1: Craft Birthright: This will double all pickups from item pedestals.
Step 2: Craft Rock Bottom: All recipes for this item require a bone heart, which can be found in secret rooms. You can get lucky and get an item pedestal in a secret room, or you can play a blood machine in the secret room until it pays out with a pedestal item, which will always drop a bone heart.
Step 3: Craft Soy Milk and then Kidney Stone. This will give an 89.5 tear delay and will destroy pretty much everything even without a damage upgrade.
Step 4: For Boss Rush/Hush, simply craft Mama Mega.
Step 5: After Boss Rush/Hush, begin saving up ingredients to craft the R Key. Note that the recipes for this item require a bone heart, so follow the secret room tip for help. Additionally, depending on the recipe you choose, it will require an additional "rare" item, such as a golden key, golden bomb, or lucky coin, so watch out for those.
Step 6: Go to Blue Baby/Lamb. If you get a Void portal, do Delirium if you are feeling confident enough. Otherwise, use the R Key and go for other marks. Do the Beast last as it will end your run after defeating it. Mega Satan can also end your run as well. There isn't much to do except leave them for last.
Optional Items:
Spoon Bender: For combat purposes.
The Mind or Blue Map: Having all secret rooms revealed is extremely helpful for bone hearts.
Black Candle: Helps the two items above work without restriction.
Psy Fly: Lets you focus while it destroys stray projectiles.
Host Hat/Pyromaniac: Explosion immunity.
< >
Showing 1-9 of 9 comments
How is it a 100% winning strategy if you probably have to restart?
NW/RL May 3, 2021 @ 6:26am 
Originally posted by Hyper Realistic Blood:
How is it a 100% winning strategy if you probably have to restart?
Once you get it, it's 100% winning
Revalopod May 3, 2021 @ 6:34am 
to add on top of that can do:
3 familiars (3 freezer babies are good) for conjoined + tractor beam + jacob's ladder
it's really cheap and easy to make and is powerful :)
orian34 May 3, 2021 @ 7:37am 
Originally posted by NW/RL:
Originally posted by Hyper Realistic Blood:
How is it a 100% winning strategy if you probably have to restart?
Once you get it, it's 100% winning
just like any infinite pick up production. Honestly it's not a great one.
If you want a 100% winning strategy: craft echo chamber, any spawning card, D20, the end.
Eprico May 3, 2021 @ 7:54am 
D1 > car battery > battery pack > school bag > D20 is pretty easy and reliable
Сосёна May 3, 2021 @ 8:19am 
Is the clicker works on this character as well? I mean can i mby collect items then switched to tainted lost?
Last edited by Сосёна; May 3, 2021 @ 8:19am
Sapatos May 3, 2021 @ 8:33am 
Oh yeah, you can also
Craft Mom's Box and hope for a "Strange Key" to do Hush even after 30 minutes (Although this is unlocked by Defeating ???, Isaac, The Lamb and Satan with Tainted Eve.)
Craft Mercurius to rush through the doors.
Last edited by Sapatos; May 3, 2021 @ 8:36am
grg May 3, 2021 @ 9:02am 
Originally posted by Winke:3:
Is the clicker works on this character as well? I mean can i mby collect items then switched to tainted lost?
clicker works in greed mode so it should work in normal just make sure to use it before you kill the boss
alex May 3, 2021 @ 9:25am 
Originally posted by Sheos:
Oh yeah, you can also
Craft Mom's Box and hope for a "Strange Key" to do Hush even after 30 minutes (Although this is unlocked by Defeating ???, Isaac, The Lamb and Satan with Tainted Eve.)
Craft Mercurius to rush through the doors.
Haven't thought of Mercurius, would definitely make this whole process much faster.
< >
Showing 1-9 of 9 comments
Per page: 1530 50

Date Posted: May 3, 2021 @ 6:23am
Posts: 9