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Now, getting dmg items is whole other story.
I agree. I mean, any teleport item/trinket/card/pill in mines will crash your game. I don't know how it could go unnoticed.
However, they aren't a no-brainer to take anymore since they come with greater risk, and are not as OP anymore (they can also drastically cut your health pool and life expectancy, many items have been nerfed)
my rule of thumb is, if i want the big damage against bosses without Boss-Armor, 2 red hearts + 2 soul hearts or 3 red hearts are safe enough for a floor 2 devil deal, otherwise try angel rooms.
If I want to get the true ending, where i need tons of HP & survivability, or i play characters that start with soul hearts (Azazel, ???), i usually go for angel deals, which have yet to fail me.
If you have a lot of money(and I do mean a lot) you can just try to spend all of your money on the donation machine to try to get multiple luck ups/angel room chance ups from it.
But with beth I do hit it. Because the higher odds of angel and how useful extra charges are.
If Angel Rooms didn't exist, Devil Deals would still work as a "take it or leave it" that can sometimes help you, but as it stands Angel Rooms are just better.
...case in point. IMO it's not even worth it if you only have 3 red hearts since you lose Angel Rooms for the rest of the run - at most, it's worth taking a Devil Deal late in the run when you have heart containers to spare and the item is actually good. At this point the only characters who seem to benefit consistently enough from Devil Deals are the Lost and the buffed Keeper. And even then, Angel Rooms still debatably have items that are just as good.
And again, Angel Rooms have Godhead and Sacred Heart. And personally I don't like Mom's Knife as you lose a lot of your room clearing power for a BIT more offensive power (compared to other meta items) on single targets, but to each their own.
I haven't unlocked Lost's stuff yet so I don't go there.
I want to add that, If i am pretty healthy on floor 2, i will ALWAYS try to go for a devil deal, the damage increase you can get from them is still just invaluable (really, every single item in there has the potential to increase your DPS, even Dead Cat -> Guppy c:) .
You might not get another deal up to FLIPPIN' FLOOR 5 (guaranteed Angel room or 50/50), which is a huge risk factor in practice, especially with the stronger enemies or alt chapters.
Your third, and maybe even second deal, if you manage to get it, is not even guaranteed to be an angel room, so you're basically stuck with damage in exchange for Health.
But, and probably the thing you want to hear, if i'd get Duality from my first devil deal, i would always go inside the angel room, they are pretty viable now, aswell. ;)