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First item room has 20/20 in it. The room before the first boss has cancer, and if you use D6 on the boss item, it turns into the wire hanger.
PJCO
Dr Fetus first floor. Can beef up Dr Fetus throught the run with D6. Also have the option to break the game with Blank card Jera. I have more fun keeping the D6 with Isaac, and rerolling the blank card.
(As if anyone would read that before posting or trying a seed... whatever.)
There have been quite a number of content updates since this thread was created, and each of them changed seed generation. If you see a AB+ seed older then May 2018 (latest content update for now), they are obsolete. It is highly unlikely you'll get what was described.
You get magic mushroom 1st floor item after rerolling mom's pad.
if the first treasure room has Lucky Foot then it works
in the first devils room there is brimstone
rest of the run is ez af
first floor has dogs tooth and the tooth door has a yellow pill and blue pill, yellow is power pill, second is tears up, boss is pin. boss drops PJs.
(dont take damage here, it has a devils room) second floor has common cold, boss is widow and drops moldy lunch, devils deal gives you ceremonial robes.
(this room also has devil deal) third floor has a shop when you blow up the shop keeper you get golden key and a soul heart. treasure room gives headless baby. boos is the peep and gives magic 8 ball. the devil gives rotten baby.
(just figure that every floor has devil, also i dont remember what he gives because i took damage) fourth floor gives infestation, the tooth door gives you a little demon that needs hearts GIVE HIM THE HEARTS!!!, fighting envy is useless, boss is chub and gives synthoil, demon guy gives you a teleport pill to the shop so you dont need a key there the shop guy (if you blow him up) gives you the head of the shopkeeper.
fifth floor has monstros lung, the boss is monstro II, it gave stim cells, devil gives you the pact, destroying mother's hand gives you a missing page.
sixth floor gives book of belial, bitten leaf, and the boss is mother.
GOOD LUCK
4MRX
BE38
3A1W
AKMA
you get fire tear but later on you get quad shot an poison tears