How to spend resources: which gourds to upgrade, which celestial pills to take?

[gungadin22000]

Being about halfway through act 3, I am wondering about two things:

1. What gourds do I upgrade? I got a few of the drink- and gourd upgrade materials, but those are quite few in number and I am worried about wasting them upgrading my starting gourd, which is still the best one I've come across so far.

2. I've so far spent all my celestial pills on defense upgrade and now have the maximum amount. Is this the best way to spend your pills or should I focus on mana instead?

Thanks in advance.

[Dre Day]

Though you will find many gourds and drinks only two gourds and two drink are upgradeable. The rest can't be upgraded but have special effects that your standard gourd/drink doesn't have. I would focus on upgrading the gourd and drink you start the game with.

As far as Celestial Pills there is no wrong choice. Health and mana are always good choices. If you are using a lot of spells or high mana spells like Pluck of Many mana would be a good choice. If you feel you are a little squish get some health upgrades.

[a passerby]

You can always reset the celestial pill upgrades. The only thing I wouldn't bother upgrading are the banes resistances since they are very situational.

As for the gourd and drinks, just upgrade the main ones. I upgraded lamb brew and it turned out to be crap. The main one on the other hand significantly increases your heals

[HiggsLP]

Imo its best to upgrade in CH1&2, then u need it the most. Later on you can find on every corner Gourds and Drinks- most Gourds with 5-6 usage.

For me it wasnt wise to upgrade four banes- those few % doesnt help much and u end up using medicine anyway. The rarest recourse is Mana(till NG+ where u can builf Mana Potion basicly;))