Lost all progress ?

[Vash the Stampede]

I started the game up today, no profile listed, all progress lost, and my graphics settings were changed. Any help ?

[Molly]

If your perks have appeared to reset to 0 completely, it is likely that your game client is having trouble reaching the Steam backend where your stats are saved. This also includes those servers (all or in part) being down for some time.

This issue should clear up over time, but try closing the game and re-launching it to force a new connection
If the issue persists try doing a steam file refresh - instructions can be found here: http://support.tripwireinteractive.com/KB/View/678-

If some of your perks have gone to 0 but not all of them or they appear to no longer be progressing at all it is likely that your stats have become corrupted and the game is failing to update them. The only way to fix this is to reset your stats on Steam. You can trigger this by opening the game console ( ` ) key by default, and typing:
resetstats "YourSteamNameHereInQuotations"

[Vash the Stampede]

It fixed itself as you mentioned. Thanks for explaining and getting back to me.