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Een vertaalprobleem melden
I'm not a native english speaker so my grammar won't be that good, but I'll try to help you.
If you want to make the item picked disappear, you have two options: 1) destroy the object; 2) hide the object (visibility).
Concerning the animation change. Set the animation speed to 0, if you haven't already. Also, if you have changed the default animation name, you should tell Construct what animation are you pointing at. Because if you have several different animations for one sprite Construct doesn't know wich one to change.
If still no go, maybe try the scirra.com forums :)