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Charisma affects Barter, which in turn affects prices, yes.
1. skills that are based on charisma, such as barter. If you have 100 barter i think charisma does nothing for price adjustment. also increases speech.
2. npc disposition when passing speech checks. Passing speech checks with npcs is factored with 2 things, your SPEECH level AND your Charisma level. If you have 100 speech you still should see differences in many cases with having 1 charisma and 10. If you are trying to pass tough speech checks use items that boost charisma along with speech for better NPC disposition and easier speech checks.
Now I don't know if NPC disposition affects barter prices or only speech checks, never checked but i'm sure someone can find a post somewhere, or check in-game real quick.