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The problem with using multiple clone labs and rapidly expanding your population is that you struggle to build enough support infrastructure to support them, and you end up with a ton of unemployed pops. You also tend to have lower quality clones and have to deal with abnormalities and a rapidly cycling population.
I think most people go with 2, but any more than that is asking for a lot of trouble. It's basically a personal preference, would you rather spend time building population to support your infrastructure or spend time building infrastructure to support your population growth?