This solution could help your RDR2 launching problem

[KREI.exe]

Find your rdr2 document folder.
After you find it, make a folder named Settings, then add manually XML file for "system.XML" inside the settings folder, after that copy and paste the code below.
To create XML file, first create a text document and change name to "system.XML"
If you can't find folder of "Setting" inside RDR2 folder, please create a folder name as "Setting" also.

you can find your rdr2 documents folder here:
YourPcName/Documents/Rockstar Games/Red Dead Redemption 2/Settings/system.XML

↑
when you create folder or file, please make sure your file follows this order.


Code:

<?xml version="1.0" encoding="UTF-8"?>

<rage__fwuiSystemSettingsCollection>
<version value="37" />
<configSource>kSettingsConfig_Auto</configSource>
<graphics>
<tessellation>kSettingLevel_Low</tessellation>
<shadowQuality>kSettingLevel_Low</shadowQuality>
<farShadowQuality>kSettingLevel_Low</farShadowQuality>
<reflectionQuality>kSettingLevel_Low</reflectionQuality>
<mirrorQuality>kSettingLevel_Low</mirrorQuality>
<ssao>kSettingLevel_Low</ssao>
<textureQuality>kSettingLevel_Low</textureQuality>
<particleQuality>kSettingLevel_Low</particleQuality>
<waterQuality>kSettingLevel_Custom</waterQuality>
<volumetricsQuality>kSettingLevel_Low</volumetricsQuality>
<lightingQuality>kSettingLevel_Low</lightingQuality>
<ambientLightingQuality>kSettingLevel_Low</ambientLightingQuality>
<anisotropicFiltering value="3" />
<dlssIndex value="0" />
<dlssQuality value="5" />
<dlssSharpen value="0.350000" />
<fsr2Index value="0" />
<fsr2Sharpen value="0.350000" />
<taa>kSettingLevel_Low</taa>
<fxaaEnabled value="false" />
<msaa value="0" />
<graphicsQualityPreset value="0.000000" />
<hdr value="true" />
<hdrIntensity value="100" />
<hdrPeakBrightness value="1000" />
<hdrFilmicMode value="true" />
<gamma value="15" />
<hdrSettingsMigrated value="true" />
</graphics>
<advancedGraphics>
<API>kSettingAPI_DX12</API>
<locked value="false" />
<asyncComputeEnabled value="false" />
<transferQueuesEnabled value="true" />
<shadowSoftShadows>kSettingLevel_Low</shadowSoftShadows>
<motionBlur value="false" />
<motionBlurLimit value="16.000000" />
<particleLightingQuality>kSettingLevel_Low</particleLightingQuality>
<waterReflectionSSR value="true" />
<waterRefractionQuality>kSettingLevel_Low</waterRefractionQuality>
<waterReflectionQuality>kSettingLevel_Low</waterReflectionQuality>
<waterSimulationQuality value="2" />
<waterLightingQuality>kSettingLevel_Medium</waterLightingQuality>
<furDisplayQuality>kSettingLevel_Medium</furDisplayQuality>
<maxTexUpgradesPerFrame value="5" />
<shadowGrassShadows>kSettingLevel_Low</shadowGrassShadows>
<shadowParticleShadows value="false" />
<shadowLongShadows value="false" />
<directionalShadowsAlpha value="false" />
<worldHeightShadowQuality value="0.000000" />
<directionalScreenSpaceShadowQuality value="0.000000" />
<ambientMaskVolumesHighPrecision value="false" />
<scatteringVolumeQuality>kSettingLevel_Low</scatteringVolumeQuality>
<volumetricsRaymarchQuality>kSettingLevel_Low</volumetricsRaymarchQuality>
<volumetricsLightingQuality>kSettingLevel_Low</volumetricsLightingQuality>
<volumetricsRaymarchResolutionUnclamped value="false" />
<terrainShadowQuality>kSettingLevel_Low</terrainShadowQuality>
<damageModelsDisabled value="false" />
<decalQuality>kSettingLevel_Low</decalQuality>
<ssaoFullScreenEnabled value="false" />
<ssaoType value="0" />
<ssdoSampleCount value="4" />
<ssdoUseDualRadii value="false" />
<ssdoResolution>kSettingLevel_Low</ssdoResolution>
<ssdoTAABlendEnabled value="true" />
<ssroSampleCount value="2" />
<snowGlints value="true" />
<POMQuality>kSettingLevel_Low</POMQuality>
<probeRelightEveryFrame value="false" />
<scalingMode>kSettingScale_Mode1o1</scalingMode>
<reflectionMSAA value="0" />
<lodScale value="0.750000" />
<grassLod value="0.500000" />
<pedLodBias value="0.000000" />
<vehicleLodBias value="0.000000" />
<sharpenIntensity value="0.000000" />
<treeQuality>kSettingLevel_Low</treeQuality>
<deepsurfaceQuality>kSettingLevel_Low</deepsurfaceQuality>
<treeTessellationEnabled value="false" />
</advancedGraphics>
<video>
<adapterIndex value="0" />
<outputIndex value="0" />
<resolutionIndex value="7" />
<screenWidth value="1280" />
<screenHeight value="960" />
<resolutionIndexWindowed value="0" />
<screenWidthWindowed value="1024" />
<screenHeightWindowed value="768" />
<refreshRateIndex value="2" />
<refreshRateNumerator value="143998" />
<refreshRateDenominator value="1000" />
<windowed value="0" />
<vSync value="1" />
<tripleBuffered value="true" />
<ReflexSettings>kSettingReflex_On</ReflexSettings>
<pauseOnFocusLoss value="true" />
<constrainMousePointer value="false" />
</video>
<videoCardDescription>NVIDIA GeForce GTX 1050 Ti</videoCardDescription>
</rage__fwuiSystemSettingsCollection>



I hope it help and works for you.

[KREI.exe]

I quoted this way from here.
https://steamcommunity.com/app/1174180/discussions/0/3593338530526969332/

I solved a problem of launching game with this solution.
Thank you someone gave me this way.

[KREI.exe]

*REMINDE

[單人跳傘隊長]

Thank you. Its work for me!

[Rey Brujo 33]

Muchas Gracias!!! Me sirvió!!! (Thank you so much!!! Its work for me!!!) :D

[Link Le Dingue]

didnt work for me