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But again - overall, ANYTHING is viable. This is a sandbox. You play in whatever way you like. In whatever way you enjoy. And nobody will hold it against you.
Short version: Yes, you can.
The reason why most non-PA builds are "low hp" is the fact that there are several cards that not only boost your damage from being low hp, but ALSO survivability. Prime example being... Serendipity(R3): below 30% health, there's a 45% chance to outright avoid any damage. Same applies to Ricochet card(18% on R3), which outright avoids damage and throws it back at the attacker. Which means you can literally run naked, without any armor at all and still survive, due to those two cards helping you avoid damage, rather than "tank" it with your non-PA armor.
Damage/Energy Resistance stats by themselves are kinda "meh". No matter how much you are able to stack via cards + food, NOTHING will beat outright avoiding damage. Or at least reducing by a specific percentage - such as Blocker(STR) that cuts all melee incoming damage by 45% on R3, as well as Fireproof(END) which cuts the same 45% on R3 off any Explosive and FIre damage that goes your way.
And at the end of the day? Best defence is a good offence. Kill before they kill you. It just so happens that those low-hp non-PA builds are also good at *killing* as much as they are good at surviving too. So the low-hp non-PA build survivability ALSO comes from outright murdering anyone before they could even look your way in the first place.
TL;DR: Full HP non-PA build is possible and is more than enough for any content. And nobody would judge you for it. It just won't perform as good as alternatives - which is PA or low-HP bloodied/unyielding.
So yes it can be done.
You will be needing SSA to be able to do end game content.. However they did just add the Engi Set which is slightly worse than SSA but could carry you until you get SSA stuff.
You'll will also need the perks that give % to not take damage and other perks that give +50 dmg resist and energy resist with no PA.. low hp also get benefits from Bolstering mods and Unyielding mods as well as nerd rage and mutations.
The opposite which is full health also has perks for it but the legendary mods are limited to Vanguard or full set Overeaters and yes you will need all 5 slots of overeaters for it too work right. This mostly best suited for using it with melee that have furious or executor mod.
You can still mix and match things because why play meta I still find uses for other mods and try to ticker with them here and there... thats the real fun like building a DOT build was kinda fun watch things die within seconds.