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In the case of any of the mentats, its a 10% chance each time you use one. Most alcohol is only a 5% chance, while some chems get up to a 35% chance each time you take one.
But there are game weapons where legendary effect is giving bonuses for each addiction you have, so they aren't always bad.
Furthermore, pretty sure you can just "wait out" the addictions. Don't they have a duration listed on the status effects tab?
Diseases have durations and can be waited out. Addictions do not, and must be cured with Addictol or a meal made from radscorpions.
Aside from stimpaks and radaway, I don't really have a problem in fallout 76.