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If you have time and patience you can try until you have what you want. For me there were only 3(?) mutations I never wanted to have (like empath for example). Other were not that bad with Class Freak perk maxed.
that is the only was to be 100% in control of the mutation process.
the rng way does eventually pan out though i dont think efficient for more then 2 mutations as the random removal rng would be 2 to 1 in favor of removing a mutation you want to keep.
player choice, save up caps and shop player vendors. or like old school players liek me, from before player vending save up ALOT of caps and find the one serum you have to have.
rad x negates mutations effects for the duration of the dose so dump all that rad x you really dont need it. yes ive heard diluted rad x does prevent some rads but i can tell you from hundreds of hours usign mutations.ive a giant stack of radaway and player camps many times have rad showers as does enclave bunker. ive not had an issue dealing with rads and not needed any kind of rad shield or rad x for a year now.
call me a rad away junkie but never had to do more then drink another purified water right after a dose...
https://www.youtube.com/watch?v=1s2pLncNbs0
RNG may be a pain, but this method is quicker then most. But serums are worth it, only with Class Freak and Starched Genes at max as DieCast stated. (Shop around you can find them as low as 300 caps each on some vendors.)
thats an awesome video! if i had little to no caps and wanted mutations... i would use this guide!