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Not necessarily, its when you get the anxious moodle you are done if i dont remember wrong. The infection it self is not a clear sign.
Normal infections will take longer to heal if untreated, but will heal. You can if you have bourbon, disinfection items or the like, take of the bandage, disinfect the wound and bandage (for faster healing) and it will go away, wont take to long to heal, just keep in mind that your fighting might be heavily affected depending on where the wound is, if its your right arm you for sure should stay low.
Infected wound can (and should) be totally ignored. Bandage once with anything, and that's IT. Disinfecting is useless, removing a bandage waste time and stop the healing that only happen if you have a bandage.
There is only a few cases when you should take care of your wound :
-deep wound require stiching, then a bandage. After a while (high skill let you know when) you can remove the stich, and re apply a bandage since it's not a weed wound anymore but a regular wound.
-Fracture take ages to heal, so it's best to use a splint. Comfrey poultice also speed up, and so having high skill when applying your splint.
-lodged bullet or glass shard require extraction before it become a deep wound.
As for zombie infection, after being hurt this will happen :
Immediately if you look in the body temp panel you could see that your body temp is inrceasing, but it's kinda annoying to check so feel free to not bother.
A few hours (4h max) after, you will get anxious for no reason other than being infected.
By half a day after max, you get queasy and lose health.
If that happen, then you are dead. Trait chance how long it take to have symptom and die by up to 50% but you will still die , so yeah don't bother taking that one.
Last note, it's 7% chance when scratched, 25% for laceration, 100% for bite. Chance is rolled when hit and that's it.
Markus' infection cleared up and went away the next day. Unfortunately day 4 was also his last day. I was sneaking behind houses without a zed in sight. Then I heard a helicopter somewhere overhead and zeds appeared from everywhere. I'm still not very good with WASD keys and struggled to keep away from the zeds that surrounded me. I must have panicked and hit a wrong key. Couldn't enter combat stance or hit anything after that. Markus got eaten. RIP.
Four days is my second longest-lived character yet. I was doing so well until the helicopter noise drew out the hordes of undead from everywhere.
EDIT: While I'm here. Set off a house alarm. Managed to get away clean. But does the house alarm eventually stop? Will it go off again if I were to return to the same house?
As for telling if you are infected, as others mentioned the Infected status on wounds doesn't matter much in base game. It's just a normal infection that makes the wound a little bit more damaging.
For the zombie infection, there are a few tells. You will get short Queasy moodles, and you will get unhappy/stress moodles. If you are a smoker the stress moodle from that trait can make it harder to tell though.