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Here is a small list of effects and items which won't work with Mei, even if Loli already told us or if it`s logic.
(I will update the list, after playing more with her):
Acid Tears,
erohW of Babylon (if a HP-up was taken),
Ipecac,
Marked,
Analog Stick,
Pencil (does only work, when entering a Room),
Evil Eye (does only work, when entering a Room),
Piercing shots (Yes, I know),
Spectral tears (Yes, I know),
Mom's Eye
Continuum (does work, but glitchy)
The Ludovico Technique
Maw of the Void
Every kind of fused bomb(!)
The worm trinkets
Loli's Commend (cutted)
Anti Gravity
Cursed Eye
Dead Dove
Dead Eye
Epic Fetus
Epiphora
Isaac's Heart
Loki's Horns
Bouncy Tears
Homing Tears
Tammy's Head
Tiny Planet
Tough Love
The Wiz
Incubus
Epiphora
Dead Eye
Pupula Duplex
Tractor Beam
Evil Eye
Dead Tooth
Eye of Greed
Glaucoma
Eye of Belial
Ghost Pepper
Large Zit
Rag Mega's Orbitals aren't affected by her shots.
The copy of you (enemy in the womb) will always shoot.
"The Soul"Champion-enemys can't push away her tears.
Her tears can still break stuff when she's not throwing them (Stuff ≠ Enemys)
Anything for the Programmer.
Noticed
This however would turn ipecac into a very risky item choice.
Another possibility would be to replicate the original arc ipecac shots had. Take the maximum distance the shot is going to travel away from mei, increase the tear height up until halfway there than reduce it to 0 on the way to said max distance, might be hard to program though.
And yes both of thos require a new tear to be spawned after the old one exploded. The new one should spawn the next time the currently empty spot passes by behind mei, otherwise it would instakill everything.
All tear variant and stat modifiers should work out of the box.
Confirmed Working Synergies
Missing / Problematic / Irrelevant Synergies
mean working or not working?