Existing Synergies

• All tear effects (fire mind, charm/frighten/poison/petrify/status effects, eye of greed, mysterious liquid, etc)
  
• Bookworm + Multishot items (20/20, inner eye, mutant spider, monstro's lung, loki's horns, mom's eye, eye sore). Conjoined is intentionally left behind, it would be way too powerful. since the ghosts can't miss.
  
• Bird's Eye
  
• Brimstone
  
• Cricket's Body
  
• Dr. Fetus
  
• Epic Fetus
  
• Ghost Pepper
  
• Jacob's Ladder
  
• Tech X
  
• Technology
  
• The Parasite

Planned Synergies

• C-section
  
• Mom's Knife
  
• Trisagion

Wanted Synergies (I don't know what to do for those items, and I'm definitely looking for suggestions)

• Godhead
  
• Homing
  
• Eye of Belial

If you want to propose a synergy for an item not mentioned here, describe what you think it should do! Disclaimer: I might use your idea, but I might also not use it.

Would love to see an Ipecac synergy that causes a much larger explosion, and makes the explosion green (like T. The Punished).
Also, Eye of the Occult could get a synergy. Could make it so that when you open up a crack, the ghost that comes out is now controlled by you (moving the same way Eye of the Occult tears move), eventually crashing down into an explosion after a delay. (Maybe just before the crashing down the ghost could seek out a nearby target, this would probably have to be short-range)

Quick ideas for the synergies you are looking for:
Godhead - where your ghosts explode, a circular damaging aura is temporarily left behind.
Homing - ghosts move much faster towards their target. (maybe a little simple)
Eye of Belial - I feel like the effect in the game is pretty cool already, creating tears at the site of the explosion which then seek out enemies.

Hope this helps in any way :)

Thank you! I'll see which of these I can implement and I'll try to do so.

wait I have an idea for homing
ghosts automatically come out of the ground

This idea is inspired by the Golden Collection mod by Preyn!
https://steamcommunity.com/sharedfiles/filedetails/?id=2642319167
Nugget:Ghosts make Nugget bursts when they explode!

Lachryphagy - the more ghosts you have in the air, the more damage you deal.

More complex idea - if a ghost is already in the air and you summon another, that ghost will seek out the ghost that is already in the air and merge with it. The explosion of this larger, merged ghost will be bigger than the normal explosion and deal increased damage.

Eye of Belial could have the ghosts spawn a hungry ghost ghost when colliding with an enemy. Alternatively they spawn double damage ghosts when colliding with an enemy.

Godhead could spawn a static tear uppon colision. This tear has a rather large aura and does not have homing.

Trisaigon could spawn trisaigon tears similar to brimstone but less brim.

The brimstone beams from the synergy arent homing even though I got sacred heart

Not sure where to put t punished ideas, but having pop keep the ghosts in the air longer would help make the item more appealing

Originally posted by The_furf_of_July:

Not sure where to put t punished ideas, but having pop keep the ghosts in the air longer would help make the item more appealing

I agree!

Does Chocolate milk synergize? I feel like Chocolate Milk could be used in a way that'll cause the ghosts to be brown, and do more damage? Maybe not 400% immediately. I suppose the more ghost charges you build up, the more damage you do, but once you lose all those charges. that bonus is gone.

idea for godhead, it creates a short-lasting godhead aura where the spirit lands, it stays there for about 3 seconds
EDIT: other ideas
anything that gives piercing: a weaker spirit spawns after it hits something, this spirit will do half your damage and will target a different enemy

lump of coal: spirit is darker now and its explosion and damage increases the farther it goes to kill a enemy

lil slugger (item from tainted treasure rooms): a sawblade comes out of the rift instead, it functions like a normal spirit but after hitting a enemy it acts like the sawblade projectile from the mod