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Early game - decent damage but limited activation options (until chain lightning). The way it's activated ends up playing similar to fireball, but with less (or no) synergies. In NG+s, false flag changes this a bit but I haven't updated this guide for NG+s.
Mid game (sac options no miniaturization) - Poison ghosts trigger from the same event, and do far more damage because of the amount of synergies available (imbue, herbalism, blight).
Late game (all skills) - miniaturization makes bone bombs just as flexible as ghosts, but hydras add even more damage versus mini. My testing has bone bomb at 10 Qn DPS whereas ghosts push as high as 1.5 Sx.
While it is "viable" skill, I would recommend ghosts for the "sacrifice for damage" play style. It just has more synergies and options once unlocked. It's possible I'm missing something and I would love to hear how you use the skill.