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Here's my preference for long endless infested missions. Steel fiber, vitality, vigor to keep you alive and give you a good health pool. Streamline and fleeting expertise for cheap casting; important after you are disrupted (which is why flow is less valuable for many missions). Rage feeds your power supply. Transient fortitude or Intensify to help with heal size and reckoning power. You run energy siphon (for lower level stuff) or steel charge (for higher level stuff where you take more damage for your rage and need more dps if melee)... really just preference. Your 8th mod can be another power strength, redirection, stretch or rush - mission dependent. If running low levels or doing speed runs I use stretch and drop vigor for rush. Bring along a carrier with sweeper and have fun.
Not completely true. Renewal is also duration based. However Renewal is unique in that duration increase doesn't extend how long Renewal lasts but actually shortens it. This is both good and bad. It's good because you get the full effect the Renewal faster. It's bad because once you hit Max HP the effect ends.
(By the ways, duration on Renewal doesn't effect how much healing you get, only how fast you heal. Shorter duration is faster than longer duration.)