Plague Inc: Evolved: Bio-Weapon (Normal)

A guide for the lethal Bio-Weapon on Normal. Yes, it works on Plague Inc.

Gameplay

The Bio-weapon. By far one of the hardest plagues in the game. This is an extremely complex plague, so I'll try to explain it as well as I can.

The Bio-Weapon starts with extra infectivity and the cure takes 18% longer than normal. It also gets a bonus 0.3 infectivity in rich countries and, similar to the Nano-Virus, the cure starts instantly (luckily, not globally). There are 4 unique abilities, and the biggest factor: Every in-game day, there is a chance that your lethality will increase naturally. Note that every day this chance gets EXPONENTIALLY higher.

Unlocked by completing the Nano-Virus.
https://steamcommunity.com/sharedfiles/filedetails/?id=2340856944

Now for the special abilities.
Gene Compression - Reduces the chance Lethality is increased.
Deactivate Modified Genes - Reduces Lethality directly.
Nucleic Acid Neutralisation - Sets the chance of lethality increasing back to default.
Upon getting all 3 of each of these abilities, you unlock the main feature of the Bio-Weapon:
Unlock Annihilate Gene - By far the deadliest trait in the game. Increases Severity and Infectivity by 40 and Lethality by 100.

Genes (ALL REQUIRED)

The Bio-Weapon is strict. All of these genes will be needed.
No exceptions.

DNA Genes

The one unique gene listed in every one of the guides. Metabolic Hijack will allow you to focus on reducing lethality without the distraction of bubbles.

Mutation Genes

Genetic Mimic is best here, as there's really not another good option.

Travel Genes

Native Biome will give us a good boost in the starting country.

Environment Genes

Xerophile will give us a further boost in the starting country, as we start in an arid climate.

Evolution Genes

ionised helix lol

The Game

Before you Begin

Allow no symptoms.. Make sure to always check on your lethality (the purple bar in the DISEASE menu, if you forgot). Even if not instructed to, if Lethality is even somewhat low (but not 0), purchase the next Deactivate Modified Genes.

Part 0.5: The Beginning

Begin in Saudi Arabia.

Part 1: lethality is no

Save up for DNA.
Under Abilities, get Gene Compression I, Gene Compression II, and Deactivate Modified Genes I. If you have no Lethality, do not get DMG (Deactivate Modified Genes).

Save up for 15 DNA.
Under Abilities, get Gene Compression III. If you didn't buy DMG last time, buy it (unless, somehow, you still have no lethality).

Save up for 15 DNA.
Under Abilities, get Nucleic Acid Neutralization I. Under Transmissions, get Air I.

Save up for 20 DNA.
Devolve all symptoms. Under Abilities, get Cold Resistance I. Under Transmissions, get Water I.

Save up for 22-25 (17-20 if you have DMG I) DNA.
Under Abilties, get Deactivate Modified Genes I if you haven't already. Get Deactivate Modified Genes II and Nucleic Acid Neutralization II.

Part 2: Spreading

Save up for 10 DNA.
Under Symptoms, get Cysts and Abcesses.

Save up for 20 DNA.
Under Abilities, get Deactivate Modified Genes III.

Save up for 20 DNA.
Under Transmissions, get Bird I.

Save up for 30 DNA.
Under Abilities, get Cold Resistance II. Under Symptoms, get Coughing.

Save up for 50 DNA.
Allow symptoms from here on out.
Under Transmissions, get Air II and Water II. Under Abilities, get Nucleic Acid Neutralization III.

Save up for 50 DNA.
Under Abilities, get Drug Resistance I and Genetic Hardening. Under Symptoms, get Sneezing.

Save up for 50 DNA.
Under Abilities, get Drug Resistance II.

Part 3: ANNIHILATE

Infect everyone.
Under Abilities, get the final trait: Unlock Annihilate Gene.

You win!

[Name_Name]

THIS MAN IS A LIFESAVER(For me, not the humans)

[kermitsakti]

no work stupid

[PhantomioDmo]

Me getting to the step 3 waiting for everyone to die and thinking at the end that i won when i realized theres still greenland not infected:

[vanilla]

Funny story: after i got DMG I i didn't get a single lethality increase until after I bought drug resistance II, so i was just , chilling with spare dna lmao

[LMR_1]

I'm not certain why, but three times in a row now the cure is completed the same time as everyone get's infected. I don't know if it's bad RNG or if I'm doing something wrong.

[someone i guess]

thy have been untrolled

[irby.erica]

nevermind it does

[irby.erica]

only guide that doesnt work

[Hi my name is Duo]

nice

[someone i guess]

cool beans