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ID 2.1.1.70
DE 8-hydroxyfuranocoumarin 8-O-methyltransferase.
AN Furanocoumarin 8-methyltransferase.
AN Furanocoumarin 8-O-methyl-transferase.
AN Xanthotoxol 8-O-methyltransferase.
AN XMT.
CA (1) S-adenosyl-L-methionine + an 8-hydroxyfurocoumarin = S-adenosyl-L-
CA homocysteine + an 8-methoxyfurocoumarin.
CA (2) S-adenosyl-L-methionine + xanthotoxol = S-adenosyl-L-homocysteine +
CA xanthotoxin.
CC -!- Converts xanthotoxol into xanthotoxin, which has therapeutic
CC potential in the treatment of psoriasis as it has photosensitizing
CC and antiproliferative activities.
CC -!- Methylates the 8-hydroxy group of some hydroxy- and methylcoumarins,
CC but has little activity on non-coumarin phenols.
CC -!- See also EC 2.1.1.69.
CC -!- Formerly EC 2.1.1.93.
//
DR BRENDA; 2.1.1.70.
DR KEGG Ligand Database for Enzyme Nomenclature; 2.1.1.70.
DR MetaCyc; 2.1.1.70.
DR IUBMB Enzyme Nomenclature; 2.1.1.70.
//

science :)[enzyme.expasy.org]