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i think the newest version is 15063 which is the creators update
you can download a new ISO here and theres an option to download the creators update if you dont have it already
https://www.microsoft.com/en-gb/software-download/windows10
you can use the new ISO to reinstall windows again if need be
Edit: the "red" part of the popup is related to my color scheme, not the nature of the message.
In general, one should not disable security settings if one doesn't know what the deal is. I got the same message you're reporting so this is what I did temporarily to allow an app's SDK to install for testing purposes. Once it was removed, I re-enabled Memory Integrity. This may or may not work for you, though.
That said, open Windows Security UI, then Device Security section. Click the link under Core Isolation and check if Memory Integrity is toggled to ON. If it is, toggle to OFF, restart machine and see if you can open either one. If so, I would see if there are other security settings or programs which may be interfering. If not, then it's guess-work.
usually such a message is shown when trying to run very old applications or 16bit on 64bit Windows and etc.
You may be onto something, though. One can search this issue and see what's out there. Here's something--suggesting to run the software architecture that matches that of your operating system.
https://www.kapilarya.com/fix-this-app-cant-run-on-your-pc-windows-10
There's plenty of other threads on this also.