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EDIT: didn't stop me from killin' Dreddy though
Potion of Purity does indeed NOT work on Haematic Drain. The only potion I know of that works is a Haematic Phylactery potion, the creation of which is originally responsible of Haematic Drain in the first place. If you end up with Haematic Drain any other way (due to an over-encrust, for example), you're at a net loss, potion-wise.
If it helps, I've clocked over 100 hours and haven't found a randomly dropped Haematic Phylactery potion yet, so I'm unsure whether they even drop at all.
EDIT:
I just checked the .xml files for spells, skills, items and monsters. The only item that clears Haematic Drain is the Phylactery potion, and the only spell that triggers Haematic Drain has a "self" target, and isn't used by monsters.
I also noticed that the price for a Phylactery potion is 0 zorkmids, I think that is a guarantee that it will never randomly show up in Brax' shop.
But I guess there can still be more "hidden" mechanics, such as the blue-outlined-y-square I mentioned earlier.