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pick up all potions, gems, soul gems, arrows, .
plates and cups and other such cra.. clutter, forget about it.
Take everything else you can carry that looks useful or is valuable, but show some restraint as it will eventually overencumber you.
In the vanilla game it is probably best to only take high value and low weight items unless you plan to make frequent trips to merchants to sell items.
Remember that having a horse allows you to travel more quickly and fast travel when overencumbered. You can gain access to a free horse in Riften doing Shadrs Debt quest.
The easiest way to manage items is with mods.
Bag of Holding
Bag of Trash
There are other mods like Bandolier, Bags and Pouches that can increase your carry weight limit.
I usually collect all food and alchemy ingredients, but I also use a mod to allow me to store those items on my Horse along with excess potions until I need it.
other than that darknight is right on about other items.
A good guide might be that if it doesn't look worth having on your person, leave it.
This is similar to what I do, except I make exceptions for potion ingredients and other crafting materials. Oh and soul gems. Got to keep Auriel's Bow enchanted continuously after all.
Of course you can smith daggers for the same idea, but the point is when you are running through dungeons, they are something you can pick up which only weighs a couple pounds and you can turn around and sell them for 180 septims while also boosting your enchanting. Provided you have massed petty souls, of course :)
Other than that, basically only jewelry, alchemy ingredients (make potions for monies), and other crafting materials (ingots, soul gems).
Once you get higher level you can pick up ebony items which sell for a ton... but at that point in the game, making money becomes stupid easy and it is more about how much running you want to do to find vendors with enough money to sell all your crap.