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Usually this sort of thing is caused by a script from a mod (which may not mean the mod is bad, per se; incorrect installation or uninstallation is often to blame). In this case, I'd assume that most of your wolves survived, the game thinks they're all still in combat, and it's unwilling to pull any further NPCs into battle until the wolves unload somehow.
The seemingly obvious solution would be to simply reload back before the point where you started spawning wolves...
Although i was screwing around after the glitch,to see if it wasnt just specific enemys and i found out that dragons do attack me,and a werewolf i had spawned long after the wolves
As for their spit attack, I'd guess they don't use it because by the time they're in combat with you, you're close enough that they'll favour their melee strikes. What happens if you let one see you, and then you regain some distance?
You can get a hint as to whether a mod is involved using MFG Console. If you select a spider with that active, down the lower right of the display you'll see the last data file in your load order to affect the creature:
http://www.nexusmods.com/skyrim/mods/44596/
Note that with proper AI processing issues (as Jaco is reporting), just going close to an enemy won't be enough to make them fight you - they'll still stand there as if they were neutral, until you actually start dealing them damage. If you're not seeing that then you don't have the same problem.