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Edit: Actually I forgot, there is an Achievement for that, I'll probably try for "Specialist" with a Defender sometime.
Defence definitely isn't a class that I've seen come up as a choice for the solo mastery achievement. However it provides a good amount of stats / health from mastery. Whilst it doesn't have a mouse one skill it does have the shield proc's and a charge attack. Colossus is a boss killer and it has good passives. It would get there but slower than others.
If you cannot finish Normal with Defence I will wonder why?
It will be a grind at times and with any solo normal runs (I have completed Normal with Hunter alone and 0 deaths), if you wanted to go into Epic you will have to go and take back a lot of mastery points to get a decent build going.
The thing that is a grind for most builds is lack of a HP pool, Defence has Rally but you would need to use it wisely.
Also pure physical/ pierce is going to make some battles drag on. As your getting into Act 3 and 4, find weapons with elemental damage and relics/ charms that can help.
I could go into everything I would do to get it through ( my favourite masteries in order are Hunter, Defence and Rune), but since I gave myself that challenge I do not wish to grind again. Apart from, I most likely would not bother with concussive blow and from an early stage go for throw weapons and do not start building up you shield and passives until after level 10, there is no need. You are a TANK.
You will not die if you build Defence correctly.
Thank you kindly for this imput ... I'm likely to need a lot of advice.
I decided to play as a "noobie", meaning no gifting, well since I lost My x years worth of TQVault some time ago I have not really bothered collecting much anyway.
I put the Beta on and decided to try out a couple of builds (not trying any of my in progress builds yet....just in case) and put my money where my mouth is. Now I am only into Act 1V and the Good, bad and ugly.
It is a plodder build, by this I mean not only do you need extra movement speed and supplement your damage output with some elemental, but no long range, AoE or decent crowd control until Batter and synergy starts getting used, which you really need a good damage output shield for.
You need to chase down enemies that split like mercury hitting the floor and these are nearly always longe range damagers - archers, mages, Kelpie (damn I hate them). Without decent speed you are a plodder. Yes, there is Shield Charge, I am expecting to use it on the Machae Grand Master Archers (but it has a 12 second cooldown).
Now its either my bad luck or RNG but I seem to have come across a lot (a damn lot) of creatures that are either carrying weapons that disrupt and suck out my energy pool or heroes (some I have not seen before) like Sark (a really annoying lizard) that do the same. You need Battle Awareness up, so running back a bit and sorting the problem should be easy, but the build is a plodder and it turns into a grind.
Good part is the build is solid, with some decent resists, a very fast attack weapon and shield, not much apart from the above is going to give much trouble.
Using a thrown weapon will wait till Ragnarok (no Batter if using a throwing shield.) and I do have my reasons for using a throw weapon in the secondary slot.
The Ugly and this turned out not to be game or the Beta.
For some reason, maybe a premonition I saved this build save folder to the desktop just before Typhon.
By the way, not having an artifact is a real pain, only 3 recipes so far dropped and none any good for this build, plus my chest armour has junk AR, luckily managed to get rid of the Stonebinder Cuffs after hunting down a decent Hallowed Helm from the merchants.
Anyway, meeting Typhon my normal way (Skies Rage ready). Run in and turn left, pick up the first 3 shrine buffs. Run in and lay down Skies Rage. The only thing need to watch out for is Life and Energy Leech, this build is good enough to withstand the Falling Rocks as long as your finger is Rally ready.
Everything going okay and then everything starts slowing down, he drops Falling Rocks which I survive but now my mouse is unresponsive and I cannot move, I hit Rally but hit by Energy Leech since I cannot move. It starts moving again but really slow, no Battle Awareness. Another lot of rocks (reminded me of being very young and trying the wrong type of substance - surreal).
As my character slowly, very slowly collapses and the headstone starts to raise - everything stops.....and then!
2 damn overlays shoot up from my anti-virus, "we have just been checking out TitanQuest.exe" and "do you know what is slowing your computer down".....what the hell!!! Most people I know believe I do not have a heartbeat since I am so chilled, but this was totally annoying. Mainly because I have my anti-virus turned off till I want it, secondly the game is whitelisted and lastly "Yes I know what slows my p.c down its ♥♥♥♥♥ like these adverts".
Will these buggering anti-virus developers stop finding back doors to keep advertising there stuff.
Damn I have written a TL/DR, I must have been annoyed.
Anyway, threw on the back up save, re-ran, killed off Typhon in about 30 seconds. Am in 1V act and merchant has just sold me a great chest piece. Hopefully the second quest will give a decent recipe.
Just gone past Medeas grove and the Lamians (cannot be bothered to farm for Ismenes gear), what is noticeable (guess I knew this) is a need to up my poison resistance.....so many damn Blightcasters from this point on.
Got a little bit more movement speed so hopefully these annoying little frogs do not have me chasing around so often.
So far Act 1V is easy. 6 mastery points and 14 attribute points in the bank. Take them a little later.
Strange when most people (including me) can see how it spikes in difficulty.
But the Machae are yet to come !!!, I will wait to use my now 9 mastery points and 15 attribute points depending on what starts to hit me the hardest.
Also, everything I am wearing has been shop bought or easily dropped, no real special items.
Apart from my little rant earlier, I am now level 39 and sitting comfortably in Ragnarok.
Machea and Dactyls just annoying little pests with this build.
I am not and will never profess to being even a good gameplayer, just that knowing this game for so long...well...foreknowledge wins out over expert finger control, but once a noobie knows a fraction of what the old timers like me know they would fly through with this build. There are 3 or 4 buttons you always need to be hovering over, which is why I have parked this one at Ragnarok, my mouse decided to give up the ghost on a second button just before Hades Palace. I had to remap again. Poor ole bugger like me trying to get used to a 3rd lot of keys.....pfffffhhhh.
Went and practiced for 20 minutes on an earlier level and went for it.
Everything this build is wearing is merchant bought apart from of course relics/ charms. Which is why (I knew from the start it would be) I have been one of those boring collect and sell everything players.
Also a big thank you to the OP, because I realised out of the 13 builds I have, only 2 are Defence, so I have copied and renamed twice and will try another 2 builds later on (new mouse and batteries required).
Also gave me another idea to try while waiting.
Its on such a quick cooldown and is low cost AOE and debuff. As soon as you invest in it, I think around level 12 - 15 range, your life changes completely.
I have 100% confidence you can clear as Defense single mastery, its a late bloomer that just keeps getting better the more you skill it up.