One fix to game crashing on startup:

[Captain Gingerbeard]

So I received a lot of issues upon first purchasing this game, especially with the game crashing on launch. This turned out to be an issue with the engine, Game Maker: Studio (GM:S). There are a lot of fixes to this now, and there's plenty of rejoice (as I'm able to play Deadbolt now, and have been for almost two weeks). However, since being able to play (due to a hardware issue, now fixed), there was one particular occasion in which the game didn't work. It seems that beside the already addressed issues, if you have more than one XBOX ONE controllers plugged into your computer at once, it causes issues with the engine, and freezes/crashes GM:S titles on startup. It's also worth noting, that this causes issues with other titles, notable Bandai Namco titles, such as One Piece Pirate Warriors 3. I found this fix after subsequently unplugging my controllers after the game didn't work, and immediately on relaunching Deadbolt, the game worked. I tried this out with other titles, such as Undertale, and it was consistent. So there's a potential fix. Also, I felt it was needed to post this, as I'm still seeing discussions being posted about the game not working. If you have a situation which is extremely conditional as this, then here's a potential fix.

TL;DR:
Plugging in more than one XBOX ONE Controllers will cause issues with this title.