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On St Louis I tried Mother. Was disappointing at first since the super mutants would have ~3 shotted her with their big guns. She lost like 1/3 HP from a burst. But after using Psycho, Afterburner Gum and Voodoo she entered ABSOLUTE BEAST MODE and proceeded to shred any mutie standing in her way while taking minimal damage, if any at all: https://imgur.com/a/AiecOxt She was great at cleaning up the trenches.
I haven't tried Shriek but I think he is going to have the same problem as Krldraav. Half drug duration probably means Psycho will run out in the mission, not sure what the duration it has but Voodoo lasted about 10-20 minutes on Mother and Psycho feels like a requirement. It was like night and day.
My current verdict is that Mother is the way to go. As long as you have drugs. She even gets a perk every 3 level and if you remove her Domesticated trait with Mutate she will deal more damage in melee, basically having no weakness, at least compared to the other deathclaws.
EDIT:
Found the duration for the drugs:
Buffout = 6 hours
Psycho = 4 hours
Voodoo = 20 minutes
Afterburner Gum = 2 Days (wtf)
So with Shriek those durations are halved. So I think it should be ok except for Voodoo. Some missions do take a long time so it's possible to exceed the 2 hour mark for Psycho but it is not as bad as I initially thought.
EDIT 2:
Disregard my previous edit, in Jefferson my drugs just run out and I'm pretty damn sure I didn't play for over 6 hours. So the duration is not real-time. If I had to guess it's probably around half, so a Psycho would last about 2 real hours. But that's just a guess. The important thing to take note of is that this severely lowers the usefulness of Shriek.
If I were to rank the deathclaws it would be:
Mother > Shaav > Shriek > Krldraav
Drugs are OK when you're facing Super Mutants with normal weapons, but drugs cannot save you when energy and heavy explosives become the norm.
[0] The only exception is when you can "stun lock" a single target in CTB, but even that stops working vs robots who are too armored for that.