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Hope this gives you a good start!
Human
Body 3
Intelligence 4
Biotech 3
Decking 3
Drone Control 3
Charisma 6
- Academic
- Gang
-Shadowrunner
Spirit Summoning 3
- Totem (I really like Leopard; Cobra and Fish are tied for second pllace, followed by Boar)
-- Coyote has a conversation option, but I don't know if it leads to anything.
This would give you a solid start using what I stated before. By doing the three missions in which you can avoid combatWalled City, Outsider, Deckcon, you can gain more Karma for fleshing out your build before you have to get in a serious fight. YMMV.
http://steamcommunity.com/sharedfiles/filedetails/?id=503910261
1 karma, unless I am missing something?
There is 220 Karma in the basic game. I have never managed to get more than 219, however. There's 1 karma kicking around that apparently I keep missing. Sometimes I get less, depending on how much my OCD is kicking in. Sometimes there is extra karma from the same mission for doing things differently. Like the Bad Qi run, mentioned above.
In bad Qi, you get one Karma for fooling the employee into giving you his ID card. You get an extra karma if instead you tell him to raise an alarm. Both methods get you access to the elevator, but the sneakier one gets you 1 more karma.[spoiler/]
Sometimes you get karma doing something that seemingly has no relevance to advancing the game per se. For example, sharing a drink with 10 Arm Ambrose nets you 1 extra karma, for no good reason that I can see.[spoiler/]
Hah! That's it! Ok, next run, 220 karma!
I'm not sure exactly what you're asking here, but if you are referring to the Karma from Ambrose ... If you have talked with him during the game, and gotten his story, near the end before heading off to Prosperity Tower, he asks if you will share a drink with him. Doing so nets you 1 karma. Maybe as a reward for listening to all his ramblings.[spoiler/]