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statwise for a phys build I try to have at least 18 toughness, 18 agi, 18str. 16-18 ego is desirable so trade doesn't hurt, and willpower is ok for the extra regen and skill tree.
I generally pick my primary stat at creation and pump most of my extra pts into that, but if you feel like you aren't hitting you can boost agi, or boost str for more hp, etc.
your last q: you can wish for level-ups, or turn off permadeath, which should let you play around with build ideas. but i recommend just trying things that seem cool and dying a lot. it's fun.
You'll have to do a lot of experimentation on your own. Also do this stuff:
1. Search and read about various builds on the forums, here
2. Check out the Steam guides. There are great ones for basic builds (see Esper), and I even wrote a beginners guide with general tips.
3. Again, dig through the forums for strategy - you'll find a ton.
Best :)
I haven't been able to make a viable agility and dodge, short blades build since the rework of that skill tree. It went from being disgustingly overpowered to useless.
For defense, you want 20+ toughness (startign with 26+ honestly is best), and a focus on either AV or DV (with a smidgen of AV). For a beginner, AV is better, so get carapace. With carapace, you'll get a lot of cold resist, so you'll also want either freezing hands or Tinker I for freeze grenades, which would mean startign with 18 int. And teleport is a great get out of death free skill for a beginner.
Mental mirror is vital in the long term for defense against confusion, which late game can hurt you bad due to being permanently confused. There's ways around that if you know about some spoilery stuff, but this is the standard defense. Will won't save you against confusion sadly, even with the higher saves and iron mind.
Strength builds get you through up to golgotha pretty quickly but drop off in usefulness considerably after that once you get a carbine. Mostly because strength builds will end up needing to have 29 strength at some point to have penetration and their top skill, which is attributes points you could have put into not dying,
Will/ego are basically a dump stat unless you go heavily into mental mutations. I've really only found will useful on truekin. Maaaybe on normal mutants if you really really hate deathroot or hornblowers or something.
Even though true kin start out with better gear, they're not a newbie race at all, they require a ton of knowledge about the game to not flop hard in the long run. Then once you've found all the spoilery stuff in the game, they end up about even xD
Edit: as for carapace being the best armor, it actually locks you out of the best. BUT don't worry about it since it's armor you only get after you've seen pretty much everything.
As for more mutation points, just pick amphibious, it's the hidden freebie 3 points xD
Bind it to a key and use when things look even kind of dicey, then wait for it to come back off cooldown and then reengage.
If you boost your inteligence in the late game, you'll get all the skill points you would have gotten if you started off that high, and the same for hp and toughness.