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How does it defeat the purpose ? Makes literally no sense.
First, if you have automation, your "entire day" is basically restocking buildings and dealing to a few people your dealers don't have room for. If I didn't use large mixes I would just stand around most times on most days.
Second, again, if you have automation, mixing 8 is no different than mixing 4. Simply order two vans of 80x4 (for 80x8) in the morning and before bed (takes less than 30 seconds); and it will keep up with your fully automated mixing/pressing building.
All you have to do is unload it. If you sleep in the same building you designate as a mixing building, you're there anyway. Again takes around a minute.
TLDR: It's not your "entire day", it takes like 2 minutes a day to set up an 8 stage mixer.
Also, you can create exponentially bigger bonuses for all 8 stages, so it's not a "defeat of purpose".
I basically wake up, unload the vans, order more vans, restock other buildings and pick up product, drop off product for mixing, do late night deliveries, unload vans, go to sleep. At some point my phone beeps and I launder more, and once in a blue moon I pick up 30-40k cash off my dealers. Doesn't take an hour, takes an in game day to do the entire thing.
Also, Steam guides would be a better place for this.
Besides just experiment with mixing outside of the game, you can reverse engineer specific effect or just look straight for best mixes, but that kinda kills the fun of mixing.
Personally to get going quickly and relatively cheap,
OGKush, Mouthwash, Cuke. is a quick cheap mix that cost $6 and sells for $72 & pretty addictive.
Once unlocked later add beans on the end. 100% addictive cost $13 sells for $97.
6 air pots with botanist is enough to keep up 3 dealers.
My early Meth is Cuke, Viagra Banana.
Cost 8$ sells for 147, not super high value but sells quickly and is quick to make using 4 labs 4 ovens 2 Chemists 3 mixers.
Enjoy.
Sure thing :) Otherwise my go to 2-mix for coke is addy + semen. Adds electrifying and long faced effects, outright doubling value of it.
It is, as of now, the absolutely best recipe for cocaine and meth, and just a few dollars off the top for weed, both for OG and purple.
As it is the same recipe for all, the same set of mixers can be used for all, and just feed it whatever you have produced.
It is a long mix though of 9 ingredients, so recommended is to have 9 mixers set up in a chain, which wouldn't be viable for a starter recipe.
Banana, Motor Oil, Cuke, Paracetamol, Gasoline, Cuke, Battery, Horse semen, Mega beans
The cost of ingredients for each product made is $44, the base prise you'll get from this is $167 for purple, $353 for meth and $756 for cocaine.