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I've never been able to select m/f for a colony ship. Only distinct species.
You may want to check your species side tab and verify the traits for these two.
You just have two species, or more precisely you have a species and a sub-species related to that species.
When you selected the red serum, it should have modified all of the members of your main species. Unfortunately, there is a bug that prevents such changes from affecting colony ships that have been built but not used and colonies that have been started but are still developing. The result is that if a scripted change to a species, like the event that modified your species, or planned genetic engineering occurs while you have unused colony ships belonging to that species or planets in the process of being colonized by that species, then you will end up with two versions of your species: one modified as it should be and the other unmodified.
When you get hit with this bug the only fix is to genetically modify your species to apply the proper template to the pops that were not modified. If it happens before you have the ability to perform genetic modification you will need to wait until you have researched the necessary technology before you can correct the problem.
In theory, when you are selecting a species while building a colony ship you should be able to see the traits of each option and so distinguish between two variants of the same species and pick the variant that you desire. Just don't make the mistake of assuming that the gender of the image displayed will match up with the species list. If you are pick one subspecies when you build a colony ship and then another subspecies is actually colonizes the planet you drop the colony ship on, then that is a bug and one that I have not seen.
Note that when you have two versions of your main species (or any species, really), the game can potentially select either one to grow new pops on your planets. Usually it correctly picks the "better" one, but sometimes it does not. So even if you colonize a planet with "red serum" humans the game may grow pops of normal humans on that planet, resulting in both being present. This is particularly annoying when your main species is involved, because with other species a planet can only grow pops that are already on the planet but any planet in your empire can grow versions of your original species even if that version is not present on the planet already.
The only way to prevent this is to force the growth on all of your planets of the variant you want to grow (to prevent the other from growing), at the cost of growth rate - assuming your government type permits this measure. Alternatively, you can accept whatever choice the game makes with the plan to fix it all later through genetic engineering, which has the advantage of not decreasing your growth rate but does cost you society research when you apply the fix.
What you can always do is to simply override the unwanted subspecies with gene modding.
Also, not sure if you ever played something like a xenophile federation builder in a medium+ size galaxy. You will end up with literally hundreds of different species, with the AI designing new and completely useless variants every week. You might still try to properly mod and consolidate individual species for a while, but sooner or later you will give up on that idea.
At that point you realize that the optimized species are only relevant for getting a headstart during the early game; afterwards it all only depends on how optimized your colonies are built, and your choices for tech, traditions, policies and such.
as result, getting single litoid or in worst case single necroid with necrofage perk, can cripple your population growth if you not noticed it in time and not took measures
playing some type of empires prevent you from taking actions and you stuck with garbage pops forever
if you want to minmax you absolutely must play auth empire, probably ever xenophobe, you can make all useless pops into livestock.
you will always grow the slave pops with the necrophage origin.
Not true you can do it with any empire but certain political faction just wont like it.
The reason the slave pops always grow when a planet has both species is that the game knows that trying to grow a necrophage pop is always the wrong decision when there is any other option. Automation in the game is pretty bad, but in some situations it does make the right choice consistently.