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You might want to recheck the lab ratio. About that point for me 1:1 or 1:2 seemed best.
Since you don't gain EP while in dilation, you need to keep doing normal runs for the EP to keep the lab increasing.
For the Challenges, all lab points into #6.
It's also possible to do fast Eternities just to increase the Eternity bonus. I have no idea what a "normal" amount of eternities is at that point.
Just keep grinding dilations until you can do the challenges, it's slow and once you're done DT will be even slower, but there will be a few power spikes on the way