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For OP, i consider Dead Cat top 5 most situational items in Isaac. On some characters it's the one of the best items in the game (both of the Lost), on others suicide sometimes.
If you are confident you can use it early game, don't pick up any additional health you get during a floor and get a free devil deal if one spawns.
During later floors its ok ?, haven't found a great use of it if you can accumulate health.
Part guppy transformation is great, but not worth picking it up only for that I think.
Makes Damocles a free take I guess, but that's very niche.
Overall, if you have extra health on the floor or items that can help you gain more ( Book of Revelations, Satanic Bible, Glyph of balance, Mitre, Relic, Binge Eater and others) I would take it, otherwise nah.
Also the #1 reason you don't take blind items in the void.