The Binding of Isaac: Rebirth

The Binding of Isaac: Rebirth

So I just got Soy Milk and Ipecac...
Its really powerful but its also really hard not to get hit. Whats some of your craziest synergies?
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Showing 1-13 of 13 comments
Doggy Davis Nov 7, 2014 @ 6:21pm 
Anti-gravity brimstone.
Medi-Wolf Nov 7, 2014 @ 6:23pm 
I got the Flaming Mind (I think it's called that) and Cricket's Body. Whenever the explosion would proc I would just get decimated because most of the other split-shots would proc the explosion as well
Krangle Nov 7, 2014 @ 6:23pm 
Soy Milk, Ipecac, Magnetic Tears, and Spoon Bender. Killed my run but it was so worth
M34T-B4G 441 Nov 7, 2014 @ 6:25pm 
Inner Eye + Mom's Knife.

Ran around shredding ♥♥♥♥♥♥♥ everything with triple knifes.
World's best Fox Nov 7, 2014 @ 6:26pm 
Brimstone and tiny moon. if you azazel (high recharge time) its pretty much a book of shadows for melee enemies
Originally posted by Doggy Davis:
Anti-gravity brimstone.
How does that work? :D
COW Nov 7, 2014 @ 6:49pm 
brimstone+ludo is crazy
Ottomic Nov 7, 2014 @ 6:52pm 
Sad Bombs, Pulse Worm, Mom's Eye Shadow, Bob's Rotten Brain. Something else that made those tears even huger.

Yes, all those effects stack. Insta riot generator. Those who survived.
Last edited by Ottomic; Nov 7, 2014 @ 6:53pm
1337Walrus Nov 7, 2014 @ 6:52pm 
Technology + Ludivcoco.

I killed Satan as Cain in that run, and I didn't really get anything good that run other than those.
Elmasta Nov 7, 2014 @ 6:52pm 
brimstone + cursed eye

Worst combination ever but beautifulll to see. It do a "vortex" and then shot like 3 sec after. You almost always miss the enmies because they have the eternity to dodge the shot but if they run into the "vortex", they get hit (like lemon mishap).
Ottomic Nov 7, 2014 @ 6:54pm 
Originally posted by xdman:
brimstone + cursed eye

Worst combination ever but beautifulll to see. It do a "vortex" and then shot like 3 sec after. You almost always miss the enmies because they have the eternity to dodge the shot but if they run into the "vortex", they get hit (like lemon mishap).

Wasn't that brimstone + antigrav?
Elmasta Nov 7, 2014 @ 6:57pm 
Originally posted by Ottomic:
Originally posted by xdman:
brimstone + cursed eye

Worst combination ever but beautifulll to see. It do a "vortex" and then shot like 3 sec after. You almost always miss the enmies because they have the eternity to dodge the shot but if they run into the "vortex", they get hit (like lemon mishap).

Wasn't that brimstone + antigrav?

I don't think I had antigrave but I'm sure I had the cursed eye.
Kazma Nov 7, 2014 @ 7:03pm 
Ipecac + Polymorpheus = 1 Hit Kill even Mom hearts
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Date Posted: Nov 7, 2014 @ 6:16pm
Posts: 13