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Edit: Okay, maybe that's just the One Die room then. It's the only one I've found, three times. My mistake.
Thats only if you get a 1
A room present in The Binding of Isaac: Rebirth possessing a purplish red tint with an embossing of a D6 on the ground. Standing on the die induces the room's effect. The number of pips visible varies and determines what effect the room will have.
1 pip - Seems to reroll all the upgrades on the player, but without the other effects of the "6" dice room (see below). There are additional effects that are not well understood.
2 pips - Rerolls the pickups in the Room like the D20.
3 pips - Rerolls the pickups in the Floor like the D20.
4 pips - Rerolls any items that have appeared on the floor but weren't previously grabbed like D6.
5 pips - Rerolls the current floor, similar to the effect of Forget Me Now.
6 pips -Seems to reroll all the upgrades present on the player at once. This does not seem to affect trinkets, pills or cards, but can change an activated item into a passive one and possibly visa-versa. Also randomizes all items on the current floor like D20.
So you just already got all the items on the floor which would explain why you didn't notice a change.
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