What cool synergies have you found so far?

[chibilibi]

I just beat Mom on my 2nd run using a really cool synergy I got.

Technology 2 + Monstro's Lung. Great combo. You can do damage with Technology 2 while charging Monstro's Lung, then you can release for a big blast of bullets. Was really fun.

[chibilibi]

I can't wait to get Brimstone + Spoon Bender.

[Conrad273]

Brimstone + Inner Eye = 3 Brimstone Lasers!

[Conrad273]

Brimstone + Hookworm(Trinket)= Wierd Lazer

[Rube Waddell]

Here's a pretty cool one:

Binding of Isaac Rebirth + A lot of people's computers = Not being able to play the game ;____;

[Leiche]

Tiny Planet + Wiggle worm = Hilarity Ensues

[Lt. Dan's Legs]

Brimstone, Inner Eye, and Mom's Eyeshadow.

Hot Pink lasers.

https://gfycat.com/FabulousKaleidoscopicAsiaticgreaterfreshwaterclam

[The Unaboner]

Quad Shot + Brimstone I got two times. It was absolutely fabulous.

[Deadshot804]

brimstone, mutant spider and common cold BEST EVER

[Shadow1fire]

http://steamcommunity.com/sharedfiles/filedetails/?id=336920414

The Ludovico Technique (new item) + Brimstone = Controllable Demonice Circle

[1337Walrus]

I think I found a synergy the game didn't instead to have. Brimstone + Ring Worm = Nothing.

[Haptic]

I don't remember the exact names, but here goes a really vague description. The item that gives you piercing shots and insane fire rate making your tears look like bullets, plus the item that makes your tears huge when you're really close to the enemy, plus the tear shield item. You become god and literally unkillable. I finished the secret room after Mom without taking a single point of damage, and there are like 30 bosses there.

[greenagent]

flying + orbit tears

[Conrad273]

Brimstone + Soy Milk= Low Damage, SUPER FAST Recharge

[Thorrin]

Jump book(forgot it's name) and the broken remote trinket. You can teleport between rooms infinitely with no recharge time. It can even take you to the secret rooms( not I AM ERROR though), pretty fun

[JacksonTriggs Fan]

I found the zip worm and the mini-bargle of Azel's to be useful, significantly widening his shot area, something I imagine would be true to anyone who got the item.

The MOST op thing I've seen, however, is "Spooky" (or any ethereal shot), combined with piercing arrows, combined with the loop-de-loop shot. Your arrows will spin around enemies six or seven times, hitting them each time, in super-fast speed. I had fear shot on them as well, which was overkill but not synergy per se.

For damage analysis, I killed the heart in about 6 seconds and [Sheolboss] burned through forms at about 1 every 5 or 6 seconds. From a distance, unlike most "quick kill" techniques. And room-clearing was a joke since I could float in rock and spam.