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That does not help.
Well, crap. I just beat Mom's Heart for the first time and unlocked Eden...I'm screwed.
Also, if you beat Mom's Heart 11 times, It Lives will permanently replace it in future runs. If you beat It Lives, you'll always have a choice of entering either Sheol or the Cathedral.
Just saying, I beat it as Maggy, kind of the most over-powered character I have ATM (Excluding Eden, I have 0 tokens since I wasted one since I was nooby. Last time I did it I had to do ESC before death screen and Alt + F4 like 5 times so I wouldn't die, it was so op. I am very unlucky in this game anyway. xD
Eh, I really don't go into curse rooms much anymore unless I am Maggy and have full yum-heart regen ready.
I do have Cain. He isn't really as op for me...it doesn't really help much.
Ok, I didn't know the other merits of Cain. Sorry...but these are the characters I do have-
Issac (Obviously), Lazarus (2nd most successful), Eve, Cain, Magdalene (most successful, beat mom's heart), and Eden.