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https://bindingofisaacrebirth.fandom.com/wiki/Book_of_Virtues
tho even after daemo explained it understand i the item still not either. i had a run with book of virtues+vortex. the whisps didnt seem to do their effects over whatever vortex nommed up
i just think some stuff works, some stuff dosnt ._.
*clicks* oo
lets pray for this synergy not be removed lol
Unicorn stump and book of shadows come to mind as literal god mode options once you've got the orbitals up, both made even more ridiculously potent with the panic button trinket. My little unicorn works just as well too, though may cost a few soul charges if used too much outside of bosses.