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Yes, I do. But I often don't quite have the health to spare to be doing that all the time.
Anyway I got pretty far yesterday (as Azazel with the tape worm, much longer range), until I accidentally picked up Soy Milk and my damage output was ruined.
General advice might be to always try and take a key to the next level so you can open the treasure room before fighting the enemies but I guess that's obvious.
Unlock more. Personally, I feel like only sometimes being able to beat Satan isn't enough to beat Greed Mode. Both itemwise (I mean, you haven't even unlocked the D6 yet, for example) and enemy wise. If you can't consistently kill at least Satan,I highly doubt you can defeat Ultra Greed.
But that's just me, personally. I seriously recommend unlocked a lot more items.
At the very least make sure your normal donation machine is at 999.
Good point, didn't think about that!
And yes, it was a polite way of saying "git gud".
Alright, thanks for the advice. I'll unlock some more stuff.
Though right now it's going swimmingly again, now that Azazel is overpowered as ♥♥♥♥ again. Guess I'll hold off on playing Azazel after this, he makes the game boringly easy now.
I could probably reach the Chest/Dark Room with ease, but I haven't unlocked it yet. I played the ♥♥♥♥ out of the original Binding of Isaac, and pretty much breezed through the Cathedral if RNGesus was even slightly on my side. But thanks anyway, I'll play some more.
My tips?
Buy a few keys if they go on sale.
Skip devil rooms, Get angel rooms.
Ez win? Unlock the technology 2, get coal from shop, get Sacred Heart/Godhead
Range really helps in Greed Mode, far more so than normal it seems. Given the size of the arena, anything that can improve your range is a godsend here while it's fairly marginal in normal runs. I was able to get to a point where I could snipe enemies off screen, which is good because enemies will surely do the same to you.
I found Judas and his Book of Belial to be quite useful as well - even though it doesn't stack in Greed, it gives you a guaranteed damage boost (in addition to his already nice starting damage) that can easily stay active for every single fight. Certain items that would typically carry you through a single room or boss fight can now take you through all of the successive waves as long as you don't stop the clock and duck out of the room.
Anyway, good luck. I'm sure you're a lot more experienced than I am, but I do see a lot of people criticizing Greed Mode (for good reasons I'm sure) or outright avoiding it, which is a shame because it can be quite fun and there's so many worthwhile unlocks to gain from there. I really appreciate that it demands different strategies and has a slightly different meta and different outright uses in some cases for some of the items you'll find.
I guess my little spiel was more just meant as encouragement to keep at it. I'll need to take my own advice of course - I'm far more terrified about the prospect of speedrunning to unlock Hush, Delirium, etc.
EDIT: Jesus, that's what I get for posting at 4:20am. I didn't realize how old this thread was. Oh well. If anyone else is struggling out there, keep the faith.
Margaret e.g. is an absolute chore to play greed mode with (just like normal mode tbh).
Yeah, that was a really pointless and stupid bump by Mr. Ping Ping. Oh well.
https://steamcommunity.com/sharedfiles/filedetails/?id=2802672398