45th challenge not working

[Zephon]

I have an issue with the TMTrainer challenge, instead of working propertly it replaces every item i find with a glitched passive that does seemingly nothing and takes the appearance of a Mama Mega. Its name is a bunch of key symbols with an h in the middle and its description is glitch particles with "Birthrig" in the end. Did anyone else encounter this? What mods could be causing this?

[aywee]

Honestly, any mod can cause issues with the game. Even cosmetic mods can use outdated version of, say, 'items.xml' file and mess the game up. So it's easier to turn off all mods.

I personally recommend leaving EID on. And also put '--luadebug' as a launch parameter for Isaac, so EID can output effects of glitched items.