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Sometimes you need to step away from the game for a while. Whenever you're totally fed up, take 5, stretch, get some water, and maybe do something else for a bit lol. It's a battle of will.
play isaac so you can learn the basic and game tir physique, what xyz item is and make opinions on what good or bad.
get ready too lose often. sometime it just happen and skill issues will always happen.
every enemys (minus some boss's) have patterns. learn them.
unless you need the speed runs marks (boss rush/hush) take your sweet time get resource. a poop/fire can be destroyed (WITHOUT A BOMB)? just destroy it. there a room you miss? just do it. analyse and macro-manage what you can, cant and what better too do next floor.
here a actual tips for secret rooms. do too how the rng work the "normal secret room" tent too be next too the same "normal room". NEVER next too a block room or room that cant spawn in a particular way (thing room for example)
the best way too bomb in is a good guessing game of 1 too 4 connected room. yes 1 cus sometime rng say f*** u and make the "normal secret room" a second "super secret room".
same rule for "super secret room" but it 1 too 1
(TLDR remember what rooms are sus)
if you have unlock Maggy/Magdalene. play her, she the best Beginner character too play.
if somehow you have judas. play him for the ultimate git gud character before you have the lost's
DON'T PLAYING AZAZEL! he may by one of the strongest character. BUT he a huge noob trap.
Best way to learn the game is by picking up the items and well, learning what they do, some are helpful overall, others are helpful situationally and others can be intentionally deprimental.
Also another important thing is to learn the enemy behaviours, specially bosses so you learn what they do and know how to dodge them.
Bombs can open secret rooms, those are almost always connected to 3 other rooms, except for the boss room. Super Secret rooms are only connected to one room, and it tends to be near the corners of the floor.
You'll notice some rocks have some X on them, blow them up, they can give you soul hearts and other goodies.
Those I feel are some of the most important beginner tip, other more complex stuff you'll learn the more you play the game.
-us any way too skip floors (onless you have a strong build for boss rush and hush but even then dont)
-combining too many "gimmick item" or volatile combos whit out protection
(exemple: monstro lunge + Eye of the Occult + pop!)
(exemple: ipecac + parasite + Cricket's Body without pyromaniac / host hat)
"guess i'l die" or "i legit cant kill" are not the only way too make your run unplayable.
there all so "i cant shoot" cus the second you do the game crash.
-taking the following item. unless its a intentional shoot in the foot or completion for dead god.
TMTRAINER, Mars, IBS, Blood Puppy, Scissors, Shard of Glass, Bumbo, Missing No. and my personal hot take of a opinion cus I personally hate the item Glitched Crown.
-ignoring mediocre item and trinket. you never know when you have a god combo/moment later. tho still be sensible sometime.
(exemple: Unicorn Stump + early blood donation machine on a floor = $$$$$$$$$)
(exemple again: Kamikaze! + pyro + lot of red hearts = INFINITE HP AND BOMBS)
(exemple AGAIN: Bob's Rotten Head / blue and red candles and more + Broken Remote = infinite teleport witch intern get you secret rooms, item room , shop and if Broken Remote gold devil/angel dills access and im error rooms FOR F***ING FREE)
do i need too go on? i can do this one all day.
-having the following stats too high or too low in some scenarios (yes im not joking)
speed (at 2.00 you can overshoot and run in too s**t and at 0.50-ish and less you outrun noting)
range (ipecac and Haemolacria get really bizarre)
shoot speed(items like spoon bender and tec X are better with as low shoot speed as possible)
EDIT: sorry for my terrible grammar.
"tactical gambling" is one of the best tool you can use.
the best example i can give is "a bomb for a bomb". in this situation you see a bomb block by rock's. get it for the "if of benefiting".
or
let say you have 10+ bombs and you get in a rome fuel of urns / mushroom / skulls / Polyps / Buckets in a way you can blow up more then 4-5 in 1 bomb. then blow them up.
let call tho's "prop rock"
these "prop rock" if blown-up have a chance too give good's or backfire in some way's.
example of the mushroom worst too best.
blow up and dmg you if you are in range of the explosion, nothing, spawn a pill, give the Liberty Cap trinket or if you are lucky give you 1 out of 3 item
mini mush (a ok item)
magic mushroom (a awesome item)
Wavy Cap (only in secret room) + (a meme item)