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dont think missing no is in greed mode though not sure
For everything else, do D6 Isaac runs and be on the look-out for items that synergize with the D6 (Habit, Sharp Plug, Wafer, 9 Volt, Battery, etc).
With the item pools you need I think it might be better just to play on regular play mode also than Greed mode.
All items only need to be picked up to show up on the collection page.
Edit: I guess it won't help as much with Mega Blast though.
I only got it by breaking Rebirth's Chest with Undefined.
Just play as Eden, she always starts with an activable item. If it's not Mega Blast, start another run.
There's 93 activables I think? Mega Blast is not less likely to show up this way than any of the others.
I'll focus on breaking Greed Mode to get Mega Blast and Succubus. I broke it once last night and I got the item that turns cards into pills well into it.