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That would be strange to see them a second time and not considered picked up or literally destroyed, but great to get your build together if necessary
I'm also curious if multiple instances of the same spacebar item stack.
Also.
Void + Glowing Hourglass might be the new Blank Card + Jera.
Correct me if I'm wrong, but isn't it the case that passive items get removed from the pool once you lay your eyes on them?
HP Up items finally have a use
all those nasty spacebar power ups!
But for passive stats, yeah, best combo
Not true.
I once got PhD is the first floor shop item and the first floor Treasure Room item.
Void is going to have a stack.
Otherwise, what happens if you Void the D6?
How things stack will have to be VERY carefully considered, otherwise OP as well.
Still calling Void+Glowing Hourglass as stupid OP.
Use it in a library.
'Oh look, now I have the effects of Satanic Bible, The Bible, Book of Shadows, and Book of Revelations. And I can gain all their effects, again, every four rooms.'
At that point, you could get to 'generate 3 spirit hearts and three black hearts every four rooms' pretty easily.
Oh, and Glowing Hourglass as a syngery would also allow for 'nuke a Bloody Penny + Blood Bank room every four rooms'.
You can't see the same item twice from the same item pool. If an item exists in at least two item pools (for instance, PHD is in both the treasure and shop pools), then you can see it twice. ;-)
Ah yes, I should have mentioned an example like that. Steam Sale springs to mind too: Get Steam Sale in store, let it there, hunt for secret room and hope for Greed to drop a second one. In fact, I remember watching, quite recently, a youtuber trying that. Might've been Hutts.
I don't think that's true, either.
I'm pretty sure fighting the Sins multiple times can give you the same drop multiple times (like Bob's Rotten Head or Steam Sale). I think the Sin item pools are the only exception to that, though.
You can (at least in Rebirth) see an item in the Shop multiple times if you haven't picked it up as well.
Source: http://bindingofisaacrebirth.gamepedia.com/Item_Pool