Best Items to unlock in repentance first?

[Goblin]

Just trying to find out what items are worth unlocking while I am grinding away at this game.

[NW/RL]

Rock bottom: beat boss rush as J+E

[mar]

Definately Revelation (Beat Mother as Bethany). Basically the angel version of Brimstone.

[HeraldOfOpera]

First off, unlock Bethany and use her to defeat Mother (the one that used to be The Witness). This is really more of a "two birds with one stone" thing because Revelation is insane and your next unlock is...

The Red Key! Do the Ascent you just unlocked, it hardly matters who because you probably won't beat The Beast on your first try. Look up how the various Tainted characters work and pick one you think you'll like; they play so differently from regular characters that any recommendation is just an opinion.

Next: do the Isaac's Awakening and Scat Man challenges. The former is a lot easier than you'd expect for a fight against Mother because Spirit Sword is just that good. Bloody Mary gives a very good trinket, but it's also really hard.

Keep unlocking Tainted characters until you've got all you can stand, and beat Mega Satan with as many of them as possible (except Tainted Lost, and not just because that's too hard). Cain, Jacob, Eden and The Forgotten all unlock challenges as well.

If at any point during this you end up with 99 pennies, spend them all in the same shop without leaving it to grab the Golden Razor and Member Card.

Always SPARE Baby Plum. I saw someone get Dead God after unlocking and picking up Plum Flute and was basically "you MONSTER! You killed her every time?!"

On the opposite end of the scale, kill Hornfel every chance you get; there's an unlock the first time and additional rewards after. Blow up the Siren's skull at least once while you're there.

Bethany's unlocks are more or less universally amazing, or at least above-par.

Jacob & Esau can be difficult to manage, but go down The Chest route at least once for Birthright and The Stairway. Maybe Boss Rush for Rock Bottom then Satan for Red Stew, maybe Greed Mode for Inner Child, but don't bother with anything else unless you actually enjoy them.

[Violeta]

The strange key to get into hush any time (Since all the tainted characters need hush)
The crane game
Fools gold rocks
Golden pennies

Soul of lilith
Soul of isaac
Soul of azazel

Reversed Justice? card
The World? Reversed card
The Lovers? Reversed card
The Emperor? Reversed card

Echo Chamber
Rock bottom
Red stew
Stairway
Inner child
Wooden chests
Blessed Penny

Member Card
Brimstone Bombs

Charged Penny
Ice Cube

Revelation
Guppy's Eye (Its soo useful)

Candy Heart

Options?
Birthright (Its so important on some tainted characters, like isaac).

[Violeta]

While not amazing I'm still glad when I get

Fruity Plum
Tinytoma
Keeper's Kin

And those first two can be useful on tainted cain as they are sooo easy to craft along with gnawed leaf. The second one is useful if you have a lot of rocks or stompy.


Horse pill
Gold pill

Are useful if you like pills or want bad phd to carry a run.

[Violeta]

Also The everything jar active item can be pretty good in greed/greedier/regular runs.

Its easy access to golden bombs/golden keys every floor, or almost every floor.

[Daegon]

Basically all Bethany unlocks.

[HeraldOfOpera]

Originally posted by Daegon:

Basically all Bethany unlocks.

I mentioned that as part of my unreasonably long post, but it's worth repeating. I don't think any other character has such consistently good unlocks; even The Lost has the oft-maligned Isaac's Heart, plus The Body and Holy Cards as mediocre at best (Tainted Lost gets them regardless of whether they're actually unlocked so he doesn't count).

[Squaredudes]

Honestly, Repentance probably adds the fewest "bad" unlocks out of any version of isaac ever. Like, almost all of the unlocks add something worthwhile or at least situational, as opposed to unlocks like isaac's tears or blood rights or marrow or the 5 billion coop babies.

[Violeta]

Originally posted by Squaredudes:

Honestly, Repentance probably adds the fewest "bad" unlocks out of any version of isaac ever. Like, almost all of the unlocks add something worthwhile or at least situational, as opposed to unlocks like isaac's tears or blood rights or marrow or the 5 billion coop babies.

I regret unlocking rotten beggers. I absolutely hate having montezuma's revenge unlocked as well as rotten hearts. And quite a few cards and souls I regret getting

Also regret having the demon shell game unlocked. Its so freaking greedy and pays out at awful rates. I'd way rather have the normal shell game, who you can at least bomb for resources which NO DEMON BEGGERS GIVE ANYMORE I might add.

Some items I'd rather not have...

Damocles (Cool idea but losing your run any time isn't. Good if your the lost)
Meat Cleaver (ugh)
Wavy Cap (I know this isn't an unlock but screw this item it makes me have motion sickness)

Glitched Crown
Yuck Heart
Vasculitis (Its not an unlock, but its still awful)

[SandTag]

Originally posted by ⛧Black⛧:

Originally posted by Squaredudes:

Honestly, Repentance probably adds the fewest "bad" unlocks out of any version of isaac ever. Like, almost all of the unlocks add something worthwhile or at least situational, as opposed to unlocks like isaac's tears or blood rights or marrow or the 5 billion coop babies.

I regret unlocking rotten beggers. I absolutely hate having montezuma's revenge unlocked as well as rotten hearts. And quite a few cards and souls I regret getting

Also regret having the demon shell game unlocked. Its so freaking greedy and pays out at awful rates. I'd way rather have the normal shell game, who you can at least bomb for resources which NO DEMON BEGGERS GIVE ANYMORE I might add.

Some items I'd rather not have...

Damocles (Cool idea but losing your run any time isn't. Good if your the lost)
Meat Cleaver (ugh)
Wavy Cap (I know this isn't an unlock but screw this item it makes me have motion sickness)

Glitched Crown
Yuck Heart
Vasculitis (Its not an unlock, but its still awful)

Damocles is at least good for lost/tainted lost.

meat cleaver with car battery and battery can pretty much oneshot anything which is kinda wack.