The Binding of Isaac: Rebirth

The Binding of Isaac: Rebirth

Bloody Mary
Most challenges have a strong orbit around a gimmick, and gives you the tools to complete them after some practice, but this challenge is really just a Lost run in disguise. There are so many items that are far more efficient and fair to replenish lost health, and Child's Heart is probably the worst. I suppose the luck is the main gimmick, but at a certain point, it's a tiny chance that you get any health back before the boss, and that health is required to get your damage up to beat Satan. If they can trade out the trinket to the fork, or charm of the vampire, the freaking tick is a better option. Yeah it's possible, but I did not slog through a hundred attempts at Speed! just to get several more iterations.
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I don't like this challenge either but that's due to my dislike for Bethany and her ♥♥♥♥♥♥ little wisps. I'd rather play as the Lost.
Mosk79 Apr 3, 2021 @ 1:06am 
Bethany is just an awful character. Is really painfull play with her.
orian34 Apr 3, 2021 @ 1:10am 
It's a difficult challenge, but you can find ways to deal with it. First is to stock up on health as much as possible, because the damage buff you gain is dependent on the total health given to the oath each floor. The more the better.

Then try to aim for good synergistic items that can solve the "no hit" starts. A really strong one is fanny pack, which gives you a ton of items after getting hit by the oath, meaning you have a high chance of getting hearts back. Keeping a sun/full health pill on you is also a good alternative
Holdupjustforfun Apr 3, 2021 @ 8:11am 
I really don’t like this challenge too, try go for angel deals and hold you find the prayer card or holy mantle, also you can try ti buy the jar of the blanket from the shop
Holdupjustforfun Apr 3, 2021 @ 8:12am 
Even a wooden cross is pretty good
Naoya Apr 3, 2021 @ 11:35pm 
I dunno... I enjoyed it, and finished it first try anyway. I think the extra damage just helped a lot with not getting hurt at the start of floors until I can get some health going
Spicybullfrog Apr 3, 2021 @ 11:43pm 
lol i got dark judas on the first floor of my bloody mary challenge so i completely circumvented it
Maniafig Apr 3, 2021 @ 11:49pm 
Back in Antibirth you could cheese this challenge by getting a Placenta and just waiting for the HP regeneration to full you up at the start of every floor. Tedious, but effective.
jayhena Apr 3, 2021 @ 11:52pm 
Originally posted by Maniafig:
Back in Antibirth you could cheese this challenge by getting a Placenta and just waiting for the HP regeneration to full you up at the start of every floor. Tedious, but effective.
someone said that apparently, they nerfed going afk for placenta to regen your full hp. haven't seen it myself so can't confirm, but apparently, it reduces your damage until you take the hp back ? probably if the game sees you regen "too much" in a single room
Jan Apr 4, 2021 @ 1:02am 
I just took my time and all opportunities to stock up on every floor as much as possible.
Sacrifice rooms, slot machines, soon enough getting more extra tools to get the run going. Bloody penny, i think mobile slot machine for one floor, fanny pack.

Btw "Spin to win" on Bethany probably is the most OP single item synergy ive seen so far.
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Date Posted: Apr 3, 2021 @ 12:15am
Posts: 10