Best characters/items?

[spider]

Hey, if there is a "Worst characters/items?" thread why not make this one?

Character: Isaac
Item: Godhead

[Nazemec]

Character: hard to say, most characters have their advantages. Overall I'd say Apollyon, since he can convert bad passives into bonus stats and virtually carry several active items at once.

Item: again, hard to say. There are several incredibly good items. Epic Fetus and Brimstone are amongst the best passives (once you know how to use them), but if you consider actives the Void has nice effects (hence why I replied Apollyon above) and D6 gives control over what you get... Don't get me started on synergies, most of the "meh" or "mostly bad" items can become incredible.

[Jeff]

Character - Isaac
Item - D6

[Megapon]

The best character in my opinion is either Cain or Eve, both start with good items that if used correctly can help you till depths
The best item in my opinion is Tech X, as i once did a full run with only that item. It's that good

[ploeppsel605]

my favourite character is the lost for some reasonand as best item i go with brimstone

[spider]

Originally posted by ploeppsel605:

my favourite character is the lost for some reasonand as best item i go with brimstone

Honestly, I'm not surprised that you picked The Lost. A little bit of an adrenaline rush can be fun sometimes

[Green]

Character - Isaac
Item - GodHead

[SEAGULL]

Character-Isaac
Item-Tech X

[Zane]

laughs in overpoweredness
Character - Azazel
Items - Mutant Spider, lots of DMG buff items(Cricket's Head, Pentagram, etc.), and Tammy's Head.
This one shots almost any boss. Only ones that survived this so far are It Lives!, Mega Satan, and Isaac/??? (It Lives! becomes bugged and can't attack if you drop him below 20% HP in that one attack. Mega Satan and Isaac/??? survive because they get invulnerability during certain parts of the fight)

[Koboss]

Character: Judas (Mostly for the fact that he has an amazing item to start even if you don’t get something good first floor)

Item: Sacred Heart

[The Cellular Level™]

This looks fun
Character- Azazel
Item- Chocolate milk+Monstro’s lung+any damage increaser

[Nazemec]

Originally posted by Zane Truesdale:

Items - Mutant Spider, lots of DMG buff items(Cricket's Head, Pentagram, etc.), and Tammy's Head.

Originally posted by Ｋ░ｉ░ｎ░ｇ 　（若:

Item- Chocolate milk+Monstro’s lung+any damage increaser

I think you both misunderstood: you're supposed to choose one item, not a synergy. Choose several if you prefer, but keep in mind you only take one at a time.

[The Cellular Level™]

Originally posted by Nazemec:

Originally posted by Zane Truesdale:

Items - Mutant Spider, lots of DMG buff items(Cricket's Head, Pentagram, etc.), and Tammy's Head.

Originally posted by Ｋ░ｉ░ｎ░ｇ 　（若:

Item- Chocolate milk+Monstro’s lung+any damage increaser

I think you both misunderstood: you're supposed to choose one item, not a synergy. Choose several if you prefer, but keep in mind you only take one at a time.

Oh ok, then
Brimstone