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Then try to find Mom's Bottle of Pills or Placebo (with another Gulp pill) in the shop
If you get gulp pill right from the start Just focus on refreshing pills in the shop until your one appears and spend your money on pills or pill drop chance raising items. Jera rune is an option, moms bottle also works. But it takes time, was one of my last achievements. Shop break with D20 ?? (Red Cube) did it for me. Farm coins and don't collect them, then D20 coins and get new batterys from the shop to keep up the rerolls. Only take nickels and dimes. Some Pick ups will be pills.
And this is the only thing in isaac i remember to use Placebo, i literally NEVER used it before & after. Pills is just Not my style of playing the game.
I eventually managed to get Marbles today by using this strat. Thanks for the help!
Omg, thank you so much. I was trying a bunch of other ways and this helped a ton